Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

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Catalog Number

ACMA00014050

Product Name

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

Category

Poly(ethylene glycol) and Poly(ethylene oxide)

Synonyms

PEG-PLGA, PEG-b-PLGA

Description

Poly(L-lactide-co-glycolide) (PLGA) is a biodegradable and biocompatible copolymer for use in biomedical research devices, such as grafts, sutures, implants.

Molecular Weight

PEG average Mn 5,000
PLGA average Mn 25,000

Molecular Formula

CH3[C2H4O]nO[(C2H2O2)x(C3H4O2)y]mH

Application

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Composition

lactide:glycolide 50:50

Features And Benefits

Good biocompatibility, low immunogenicity and good degradability.
Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Form

powder

Packaging

1 g in glass bottle

Storage Temperature

2-8°C

MSDS

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COA

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Spec Sheet

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