Poly(ethylene glycol) dithiol - Materials / Alfa Chemistry

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Poly(ethylene glycol) dithiol

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Catalog Number

ACMA00013979

Product Name

Poly(ethylene glycol) dithiol

Category

Poly(ethylene glycol) and Poly(ethylene oxide)

IUPAC Name

2-(2-sulfanylethoxy)ethanethiol

Molecular Weight

138.3g/mol

Molecular Formula

C4H10OS2

Canonical SMILES

C(CS)OCCS

InChI

InChI=1S/C4H10OS2/c6-3-1-5-2-4-7/h6-7H,1-4H2

InChI Key

CNDCQWGRLNGNNO-UHFFFAOYSA-N

Application

Poly(ethylene glycol) dithiol serves a crucial role as a versatile cross-linking reagent with thiol reactivity. It is instrumental in applications such as mucoadhesive drug delivery, where its thiol functionalization facilitates strong adherence capabilities. Additionally, it is used in the synthesis of dithiol terminated amphiphilic diblock copolymers, like bidentate dithiol-poly(ethylene glycol)-poly(d,l-lactide) (SH2-PEG-PDLLA), showcasing its ability to bridge different polymeric structures. Moreover, Poly(ethylene glycol) dithiol is particularly effective in functionalizing gold nanoparticles through a simple ligand exchange process, thereby enhancing the functional versatility of nanoparticles in various biomedical applications.

Complexity

28.9

Covalently-Bonded Unit Count

EC Number

218-421-5

Exact Mass

138.017307g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

138.017307g/mol

NSC Number