CAS 25322-68-3 Poly(ethylene glycol), average Mn 300

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Poly(ethylene glycol), average Mn 300

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Catalog Number

ACM25322683-41

CAS Number

25322-68-3

Product Name

Poly(ethylene glycol), average Mn 300

Structure

Category

Polymers

Synonyms

PEG

Description

Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation.

Molecular Weight

Mn 285-315
average Mn 300

Canonical SMILES

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI Key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

Melting Point

−15-−8 °C (lit.)

Density

1.125 g/mL at 25 °C

Application

Activated PEG derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. In addition to PEGylation, activated PEG derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity.

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Form

viscous liquid

MDL Number

MFCD00081839

Packaging

Packaging
20 kg in poly drum
1 kg in glass bottle
5, 250, 500 g in glass bottle

Refractive Index

n20/D 1.463

MSDS

Download MSDS