CAS 25249-16-5 Poly(2-hydroxyethyl methacrylate)

NAVIGATION

Poly(2-hydroxyethyl methacrylate)

PRICE INQUIRY

Catalog Number

ACM25249165-3

CAS Number

25249-16-5

Product Name

Poly(2-hydroxyethyl methacrylate)

Structure

Category

Hydrophilic Polymers; Self Assembly and Lithography; Polymers

Synonyms

Poly(2-HEMA),Poly-HEMA

Description

Solid Poly(2-hydroxyethyl methacrylate) (pHEMA) is brittle, while pHEMA hydrogel is a soft material. Glass transition temperature for pHEMA hydrogels is reduced by increasing a content of water in the matrix. Macromolecular properties in pHEMA are characterized by non-covalent interactions of hydrogen-bonds among the polymer chains as well as the hydrated water molecules. The presence of polar groups of hydroxyl and carboxyl on each repeat unit makes this polymer compatible with water. The hydrophobic a-methyl groups of the backbone convey hydrolytic stability to the polymer and enhance mechanical strength of the polymer matrix.

IUPAC Name

2-hydroxyethyl 2-methylprop-2-enoate

Molecular Weight

130.14g/mol

Molecular Formula

(C6H10O3)n

Canonical SMILES

CC(=C)C(=O)OCCO

InChI

1S/C6H10O3/c1-5(2)6(8)9-4-3-7/h7H,1,3-4H2,2H3

InChI Key

WOBHKFSMXKNTIM-UHFFFAOYSA-N

Boiling Point

67 °C @ 3.5 mm Hg;250 °C (calculated)

Melting Point

FP: -12 °C

Flash Point

97 °C (closed cup);97 °C c.c.

Density

1.034 @ 25 °C/4 °C;1.07 g/cm³

Solubility

0.77 M;Miscible with water and soluble in common org solvents;Solubility in water: miscible

Application

pHEMA scaffolds are used in tissue engineering. It can be used in hydrogels for biomedical applications, as sorbents for metal ions.pHEMA has been used in applications such as soft contact lenses, in drug delivery systems, and in kidney dialysis membranes.Nanoparticles of pHEMA may be employed as a carrier for controlled delivery of anticancer and antitumor drugs.

Storage

room temp

Color/Form

Clear mobile liquid

Complexity

118

Covalently-Bonded Unit Count

EC Number

212-782-2;927-388-2

Exact Mass

130.062994g/mol

Form