CAS 948-65-2 2-Phenylindole - Materials / Alfa Chemistry

NAVIGATION

2-Phenylindole

PRICE INQUIRY

Catalog Number

ACM948652

CAS Number

948-65-2

Product Name

2-Phenylindole

Structure

Category

Ligands for Functional Metal Complexes

IUPAC Name

2-phenyl-1H-indole

Molecular Weight

193.24g/mol

Molecular Formula

C14H11N

Canonical SMILES

C1=CC=C(C=C1)C2=CC3=CC=CC=C3N2

InChI

InChI=1S/C14H11N/c1-2-6-11(7-3-1)14-10-12-8-4-5-9-13(12)15-14/h1-10,15H

InChI Key

KLLLJCACIRKBDT-UHFFFAOYSA-N

Melting Point

190.5 °C

Solubility

0.7 [ug/mL]

Application

2-Phenylindole is an off-white to beige or slightly green powder that serves as a versatile reactant in various chemical processes and product formulations. It is utilized in the preparation of oxopyrrolidine analogs through iodine-catalyzed Markovnikov addition, as well as in the development of tryptophan dioxygenase inhibitors, specifically pyridyl-ethenyl-indoles, which are explored as potential anticancer immunomodulators. Additionally, 2-Phenylindole plays a role in the production of organic light-emitting diodes (OLEDs) and contributes to research into anti-inflammatory agents and possible cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibitors. It is further investigated for its potential applications in cancer and malaria therapies, serving as a foundation for antifungal and antibacterial agents and fluorescent probes. Moreover, 2-Phenylindole is involved in difluorohydroxylation and Mannich-type reactions, showcasing its wide range of functionalities in chemical synthesis and therapeutic research.

Complexity

207

Covalently-Bonded Unit Count

EC Number

213-436-3

Exact Mass

193.089149g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

alpha-phenylindole;alpha-phenylindole potassium salt

Monoisotopic Mass