PAMAM dendrimer, ethylenediamine core, generation 0.5 solution

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Catalog Number

ACMA00015931

Product Name

PAMAM dendrimer, ethylenediamine core, generation 0.5 solution

Category

Dendrimers

Description

This product is a poly(amidoamine) that is categorized under the class of dendritic polymers, which can be prepared by a two-step reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular branched upon branched pattern. PAMAM is majorly used as a high capacity chelating agent.

Molecular Weight

1269.04

Molecular Formula

[NH2(CH2)2NH2]:(G=0.5);dendri PAMAM(NHCH2CH2COONa)8

Canonical SMILES

[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CCN(CCNC(=O)CCN(CCN(CCC(=O)NCCN(CCC([O-])=O)CCC([O-])=O)CCC(=O)NCCN(CCC([O-])=O)CCC([O-])=O)CCC(=O)NCCN(CCC([O-])=O)CCC([O-])=O)CCC([O-])=O

InChI

1S/C46H80N10O20.8Na/c57-35(47-13-29-51(21-5-39(61)62)22-6-40(63)64)1-17-55(18-2-36(58)48-14-30-52(23-7-41(65)66)24-8-42(67)68)33-34-56(19-3-37(59)49-15-31-53(25-9-43(69)70)26-10-44(71)72)20-4-38(60)50-16-32-54(27-11-45(73)74)28-12-46(75)76;;;;;;;;/h1-34H2,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,61,62)(H,63,64)(H,65,66)(H,67,68)(H,69,70)(H,71,72)(H,73,74)(H,75,76);;;;;;;;/q;8*+1/p-8

InChI Key

HLBBXYHSZWSLRS-UHFFFAOYSA-F

Boiling Point

65 °C

Density

0.86 g/mL at 25 °C

Application

They adopt nanometer-scale dimensions, and can be ideal candidates for drug delivery, gene transfection applications.

Features And Benefits

Low toxicity and good biocompatibility.

Form

20 wt.% in methanol, Contains 8 surface carboxylate groups