CAS 756526-02-0 5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester

NAVIGATION

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester

PRICE INQUIRY

Catalog Number

ACM756526020-1

CAS Number

756526-02-0

Product Name

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester

Category

Polymers

IUPAC Name

3-[2-[2-[2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid

Molecular Weight

663.8g/mol

Molecular Formula

C34H49NO12

Canonical SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)O

InChI

InChI=1S/C34H49NO12/c36-33(37)9-11-39-13-15-41-17-19-43-21-23-45-25-26-46-24-22-44-20-18-42-16-14-40-12-10-35-34(38)47-27-32-30-7-3-1-5-28(30)29-6-2-4-8-31(29)32/h1-8,32H,9-27H2,(H,35,38)(H,36,37)

InChI Key

VYXGUCLTEWCVRY-UHFFFAOYSA-N

Application

5,8,11,14,17,20,23,26-Octaoxa-2-azanonacosanedioic acid 1-(9H-fluoren-9-ylmethyl) ester serves as a versatile tool in the synthesis of protein-antiviral compound conjugates through pegylation reactions. This product, featuring an Fmoc-protected amine and a terminal carboxylic acid, is designed to facilitate the efficient linking of molecules in aqueous environments. The hydrophilic polyethylene glycol (PEG) spacer enhances solubility, enabling smoother reactions and product handling. By removing the Fmoc group under basic conditions, a free amine is revealed, which is crucial for subsequent conjugation steps. Additionally, the terminal carboxylic acid is reactive with primary amine groups, forming stable amide bonds in the presence of activators such as EDC or HATU, thereby allowing precise and robust molecular interactions.

Complexity

783

Covalently-Bonded Unit Count

Exact Mass

663.325476g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

663.325476g/mol

Rotatable Bond Count

XLogP3

1.4