CAS 118-82-1 N-Acetyl-L-leucine - Materials / Alfa Chemistry

NAVIGATION

N-Acetyl-L-leucine

PRICE INQUIRY

Catalog Number

ACM118821-2

CAS Number

118-82-1

Product Name

N-Acetyl-L-leucine

Category

Monomers

Synonyms

Leucine, N-acetyl-, L-;L-Leucine, N-acetyl-;N-Acetyl-L-lenucine;n-acetyl-l-leucin;(S)-N-Acetylleucine;(S)-2-ACETYLAMINO-4-METHYL-PENTANOIC ACID;N-ALPHA-ACETYL-L-LEUCINE;N-ALPHA-ACETYL-DL-LEUCINE

Description

DryPowder; Liquid; OtherSolid, Liquid

IUPAC Name

2,6-ditert-butyl-4-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]phenol

Molecular Weight

424.7g/mol

Molecular Formula

C29H44O2

Canonical SMILES

CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C

InChI

InChI=1S/C29H44O2/c1-26(2,3)20-14-18(15-21(24(20)30)27(4,5)6)13-19-16-22(28(7,8)9)25(31)23(17-19)29(10,11)12/h14-17,30-31H,13H2,1-12H3

InChI Key

MDWVSAYEQPLWMX-UHFFFAOYSA-N

Melting Point

187-190°C(lit.)

Application

N-Acetyl-L-leucine, a white crystalline powder, serves an important role in biomedical applications. It is utilized in the development of small molecule inhibitors targeting anti-apoptotic Bcl-2 family proteins, which are crucial for regulating cell death processes. Additionally, it is used in the synthesis of amphiphilic copolymers, which incorporate hydrophobic amino acids and oligopeptide side chains. These copolymers are instrumental in optical tumor imaging performed in vivo. As the N-acetyl derivative of L-leucine, distinct reaction processes such as C-H activation and solution phase peptide synthesis, often employing catalysts, are integral to its application in peptide synthesis.

Complexity

480

Covalently-Bonded Unit Count

EC Number

204-279-1

Exact Mass

424.334131g/mol

Formal Charge

Hazard Statements

Heavy Atom Count

MeSH Entry Terms

4,4'-methylenebis(2,6-di-tert-butylphenol)