Lithium Phenyl(2,4,6-trimethylbenzoyl)phosphinate

Name: Lithium Phenyl(2,4,6-trimethylbenzoyl)phosphinate
SKU: ACM85073194
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Catalog NumberACM85073194

CAS Number85073-19-4

CategoryPolymerization Initiators; Polymerization Reagents

IUPAC Name

lithium;phenyl-(2,4,6-trimethylbenzoyl)phosphinate

Molecular Weight

294.2g/mol

Molecular Formula

C16H16LiO3P

Canonical SMILES

[Li+].CC1=CC(=C(C(=C1)C)C(=O)P(=O)(C2=CC=CC=C2)[O-])C

InChI

InChI=1S/C16H17O3P.Li/c1-11-9-12(2)15(13(3)10-11)16(17)20(18,19)14-7-5-4-6-8-14;/h4-10H,1-3H3,(H,18,19);/q;+1/p-1

InChI Key

JUYQFRXNMVWASF-UHFFFAOYSA-M

Application

Lithium Phenyl(2,4,6-trimethylbenzoyl)phosphinate serves as a water-soluble, cytocompatible Type I photoinitiator ideal for polymerizing hydrogels and other polymeric materials. Its use is particularly advantageous in biological applications due to its enhanced water solubility and increased polymerization rates when exposed to 365 nm light. Furthermore, it can absorb at 400 nm, facilitating polymerization with visible light. These features enable more efficient polymerization kinetics, allowing for cell encapsulation with lower initiator concentrations and longer wavelengths of light, which can reduce toxicity and improve cell viability. While LAP generates free radicals under bioprinting conditions that may be cytotoxic and mutagenic, its concentration is crucial for determining the mechanical strength of 3D-printed scaffolds. Typically, a concentration of 0.05%-1% is used, with 0.1% providing the highest elastic modulus, resulting in superior mechanical properties and excellent biocompatibility.

Complexity

394

Covalently-Bonded Unit Count

Exact Mass

294.09971g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

lithium phenyl-2,4,6-trimethylbenzoylphosphinate;phenyl-2,4,6-trimethylbenzoylphosphinate

Monoisotopic Mass

294.09971g/mol

Rotatable Bond Count