CAS 174669-73-9 2-Fluoropyridine-3-boronic acid

NAVIGATION

2-Fluoropyridine-3-boronic acid

PRICE INQUIRY

Catalog Number

ACM174669739-1

CAS Number

174669-73-9

Product Name

2-Fluoropyridine-3-boronic acid

Structure

Category

Salt

IUPAC Name

(2-fluoropyridin-3-yl)boronic acid

Molecular Weight

140.91g/mol

Molecular Formula

C5H5BFNO2

Canonical SMILES

B(C1=C(N=CC=C1)F)(O)O

InChI

InChI=1S/C5H5BFNO2/c7-5-4(6(9)10)2-1-3-8-5/h1-3,9-10H

InChI Key

YUHZIUAREWNXJT-UHFFFAOYSA-N

Purity

95%

Application

2-Fluoropyridine-3-boronic acid is a versatile white powder reactant primarily used in heterocyclization with α-oxocarboxylic acids and Suzuki-Miyaura coupling reactions. Furthermore, it serves as a valuable precursor for the synthesis of biologically active molecules. These include heteroaryl benzylureas, which inhibit glycogen synthase kinase 3, as well as carboxyindoles that target HCV NS5B polymerase. Additionally, it is used in the production of pyrazolyl- and thienyl-aminohydantoins, known for their BACE1 inhibitory activity.

Complexity

114

Covalently-Bonded Unit Count

Exact Mass

141.039737g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

Hexanes;Isohexanes

Monoisotopic Mass

141.039737g/mol

Rotatable Bond Count