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  • Ethyl cellulose, viscosity 45-55mPa.s, 5 % in toluene/isopropanol 80:20

  • Ethyl cellulose, viscosity 45-55mPa.s, 5 % in toluene/isopropanol 80:20

    Catalog Number
    ACM9004573-12
    CAS Number
    9004-57-3
    Product Name
    Ethyl cellulose, viscosity 45-55mPa.s, 5 % in toluene/isopropanol 80:20
    Category
    Polymers
    IUPAC Name
    (2R,3R,4S,5S,6R)-5-[(2S,3R,4S,5S,6R)-4,6-bis(ethoxymethyl)-3,5-dihydroxyoxan-2-yl]oxy-3-ethoxy-6-(hydroxymethyl)oxane-2,4-diol
    Molecular Weight
    440.5g/mol
    Molecular Formula
    C19H36O11
    Canonical SMILES
    CCOCC1C(C(OC(C1O)OC2C(OC(C(C2O)OCC)O)CO)COCC)O
    InChI
    InChI=1S/C19H36O11/c1-4-25-8-10-13(21)12(9-26-5-2)29-19(14(10)22)30-16-11(7-20)28-18(24)17(15(16)23)27-6-3/h10-24H,4-9H2,1-3H3/t10-,11+,12+,13-,14+,15-,16+,17+,18+,19-/m0/s1
    InChI Key
    GJQHNBFXPPDVQM-KSQRYXQLSA-N
    Melting Point
    240-255 °C
    Density
    1.07-1.18
    Solubility
    INSOL IN GLYCERIN AND PROPYLENE GLYCOL;FREELY SOL IN MIXT OF AROMATIC HYDROCARBONS WITH ALCOHOL;Has an ethyl degree of substitution (DS) in the range of ~2.2 - 2.7. ... water soluble at DS ~1.2 ... Above a DS of ca 2.5, soluble in many polar solvents.;Soluble in most organic liquids
    Application
    Ethyl cellulose, with a viscosity of 45-55 mPa.s at a 5% concentration in toluene/isopropanol (80:20), serves multiple roles across various industries by utilizing its unique properties as a low-density polymer. It functions predominantly as a binder, film former, and thickener. In pharmaceutical applications, ethyl cellulose is primarily employed as a hydrophobic coating agent for tablets and granules, enhancing their stability and modifying drug release rates. Its ability to form water-insoluble films, whether used alone or modified with additives like hypromellose or plasticizers, makes it valuable in producing durable, controlled-release coatings. Furthermore, ethyl cellulose facilitates the production of hard, low-friability tablets and is instrumental in drug microencapsulation, which regulates release rates based on the microcapsule's wall thickness and surface area. Beyond pharmaceuticals, ethyl cellulose's thickening and stabilizing qualities are also leveraged in topical formulations, cosmetics, and food products. Its diverse solubility in various solvents allows for a wide range of varnish formulations, underscoring its versatility across multiple domains.
    Color/Form
    WHITE NEEDLES FROM BENZENE;FREE-FLOWING, WHITE TO LIGHT TAN POWDER;AVAILABLE COMMERCIALLY AS CLEAR FILM OR SHEET;White, granular, thermoplastic solid
    Complexity
    481
    Covalently-Bonded Unit Count
    1
    EC Number
    618-384-9
    Exact Mass
    440.225762g/mol
    Formal Charge
    0
    Heavy Atom Count
    30
    Log P
    5.5 (LogP)
    Monoisotopic Mass
    440.225762g/mol
    Other Experimental
    MEDIUM-TYPE VISCOSITY GRADE CONTAINS LESS THAN 46.5% ETHOXY GROUPS; STANDARD-TYPE VISCOSITY GRADE CONTAINS 46.5% OR MORE;Lowest density of commmercial cellulose plastics; high dielectric strength; softening point 100-130 °C;Inert to alkalies and dilute acids; compatible with resins, waxes, oils, and plasticizers;ODORLESS & TASTELESS /CELLULOSE ETHERS/;The ethoxyl content of ethyl cellulose affects thermal behavior.;Sol in ethyl acetate, ethylene dichloride, benzene, toluene, xylene, butyl acetate, acetone, methanol, ethanol, butanol, carbon tetrachloride. /47% product/;FREELY SOL IN CHLOROFORM, CYCLOHEXANE FREELY SOL IN METHYL ACETATE /MEDIUM VISCOSITY/;/Ethyl cellulose/ forms films of good thermostability and excellent flexibility and toughness.
    Refractive Index
    Index of refraction: 1.47;FORMS FILMS THAT HAVE REFRACTIVE INDEX OF ABOUT 1.47
    Rotatable Bond Count
    11
    Stability
    Very stable chemically /Cellulose ethers/
    XLogP3
    -2.4
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