CAS 9004-57-3 Ethyl Cellulose [9-11mPa·s, 5% in Toluene + Ethanol (80:20) at 25°C]

NAVIGATION

Ethyl Cellulose [9-11mPa·s, 5% in Toluene + Ethanol (80:20) at 25°C]

PRICE INQUIRY

Catalog Number

ACM9004573-17

CAS Number

9004-57-3

Product Name

Ethyl Cellulose [9-11mPa·s, 5% in Toluene + Ethanol (80:20) at 25°C]

Category

Polymers

IUPAC Name

(2R,3R,4S,5S,6R)-5-[(2S,3R,4S,5S,6R)-4,6-bis(ethoxymethyl)-3,5-dihydroxyoxan-2-yl]oxy-3-ethoxy-6-(hydroxymethyl)oxane-2,4-diol

Molecular Weight

440.5g/mol

Molecular Formula

C19H36O11

Canonical SMILES

CCOCC1C(C(OC(C1O)OC2C(OC(C(C2O)OCC)O)CO)COCC)O

InChI

InChI=1S/C19H36O11/c1-4-25-8-10-13(21)12(9-26-5-2)29-19(14(10)22)30-16-11(7-20)28-18(24)17(15(16)23)27-6-3/h10-24H,4-9H2,1-3H3/t10-,11+,12+,13-,14+,15-,16+,17+,18+,19-/m0/s1

InChI Key

GJQHNBFXPPDVQM-KSQRYXQLSA-N

Melting Point

240-255 °C

Density

1.07-1.18

Solubility

INSOL IN GLYCERIN AND PROPYLENE GLYCOL;FREELY SOL IN MIXT OF AROMATIC HYDROCARBONS WITH ALCOHOL;Has an ethyl degree of substitution (DS) in the range of ~2.2 - 2.7. ... water soluble at DS ~1.2 ... Above a DS of ca 2.5, soluble in many polar solvents.;Soluble in most organic liquids

Application

Ethyl Cellulose [9-11mPa·s, 5% in Toluene + Ethanol (80:20) at 25°C] is primarily used as a versatile binder, film former, and thickener. It is an ethyl ether of cellulose, notable for its solubility in various solvents, enabling the formulation of water-insoluble films. These properties make it a valuable component in pharmaceutical, cosmetic, and food applications. In pharmaceuticals, ethyl cellulose serves as a hydrophobic coating agent for tablets and granules, facilitating modified release, taste masking, and stabilization of formulations. It is instrumental in controlling drug release through diffusion and can enhance the structural integrity of compressed dosage forms. Ethylcellulose is also employed in microencapsulation, influencing drug release based on wall thickness and surface area of microcapsules. In cosmetic and topical formulations, it acts as a thickening agent, provided an appropriate solvent is used, and has been explored as a stabilizer for emulsions. Its low moisture absorption and excellent dimensional stability further extend ethyl cellulose's application across multiple industries.

Color/Form

WHITE NEEDLES FROM BENZENE;FREE-FLOWING, WHITE TO LIGHT TAN POWDER;AVAILABLE COMMERCIALLY AS CLEAR FILM OR SHEET;White, granular, thermoplastic solid

Complexity

481

Covalently-Bonded Unit Count

EC Number

618-384-9

Exact Mass

440.225762g/mol

Formal Charge

Heavy Atom Count

Log P

5.5 (LogP)

Monoisotopic Mass

440.225762g/mol

Other Experimental

MEDIUM-TYPE VISCOSITY GRADE CONTAINS LESS THAN 46.5% ETHOXY GROUPS; STANDARD-TYPE VISCOSITY GRADE CONTAINS 46.5% OR MORE;Lowest density of commmercial cellulose plastics; high dielectric strength; softening point 100-130 °C;Inert to alkalies and dilute acids; compatible with resins, waxes, oils, and plasticizers;ODORLESS & TASTELESS /CELLULOSE ETHERS/;The ethoxyl content of ethyl cellulose affects thermal behavior.;Sol in ethyl acetate, ethylene dichloride, benzene, toluene, xylene, butyl acetate, acetone, methanol, ethanol, butanol, carbon tetrachloride. /47% product/;FREELY SOL IN CHLOROFORM, CYCLOHEXANE FREELY SOL IN METHYL ACETATE /MEDIUM VISCOSITY/;/Ethyl cellulose/ forms films of good thermostability and excellent flexibility and toughness.

Refractive Index

Index of refraction: 1.47;FORMS FILMS THAT HAVE REFRACTIVE INDEX OF ABOUT 1.47

Rotatable Bond Count

Stability

Very stable chemically /Cellulose ethers/

XLogP3

-2.4

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