Catalog Number
ACM82942265-1
Product Name
4-(Dimethylamino)pyridine, polymer-bound
Description
extent of labeling: ~3.0 mmol/g "DMAP" loading, matrix crosslinked with 2% DVB
Application
Polymer-bound 4-(dimethylamino)pyridine is used as a supported base in the Michael addition and nitrous acid elimination process step involved in the synthesis of thiophene-2-carboxylates using β-nitroacrylates as starting materials, under a general and efficient continuous flow-based protocol. It also serves as a supported catalyst in the preparation of ω-nitro esters starting from cyclic 2-nitro ketones under solid heterogeneous catalysis.(5)
Hazard Class
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Hazard Statements
H315 - H319 - H335
Personal Protective Equipment
Eyeshields, gloves, type N95, type P1 (EN143) respirator filter
Precautionary Statements
P302 + P352 - P305 + P351 + P338