CAS 444120-91-6 2-Chloropyridine-5-boronic acid

NAVIGATION

2-Chloropyridine-5-boronic acid

PRICE INQUIRY

Catalog Number

ACM444120916-1

CAS Number

444120-91-6

Product Name

2-Chloropyridine-5-boronic acid

Structure

Category

Salt

Synonyms

2-CHLORO-5-PYRIDYL BORONIC ACID;2-CHLORO-5-PYRIDINEBORONIC ACID;2-CHLOROPYRIDIN-5-YLBORONIC ACID;2-CHLOROPYRIDINE-5-BORONIC ACID;(6-CHLOROPYRIDIN-3-YL)BORONIC ACID;6-CHLOROPYRIDIN-3-YL-3-BORONIC ACID;6-CHLOROPYRIDINE-3-BORONIC ACID;6-CHLORO-3-PYRIDINYLBOR

IUPAC Name

(6-chloropyridin-3-yl)boronic acid

Molecular Weight

157.36g/mol

Molecular Formula

C5H5BClNO2

Canonical SMILES

B(C1=CN=C(C=C1)Cl)(O)O

InChI

InChI=1S/C5H5BClNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3,9-10H

InChI Key

WPAPNCXMYWRTTL-UHFFFAOYSA-N

Purity

98%

Application

2-Chloropyridine-5-boronic acid is a versatile white to off-white solid utilized in a variety of chemical synthesis applications. It plays a crucial role in the formation of biologically significant compounds, such as 3-arylcoumarins, through the Suzuki reaction with 3-chlorocoumarin. Additionally, it serves as a key substrate in the synthesis of 11-(pyridinylphenyl)steroids, which exhibit a progesterone agonist/antagonist profile. The compound is also instrumental in the preparation of α-secondary and tertiary pyridines by reacting with pyridotriazoles, as well as in the palladium-catalyzed α-arylation of saturated cyclic amines and N-methyl amines, demonstrating its importance in facilitating advanced chemical transformations.

Complexity

114

Covalently-Bonded Unit Count

Exact Mass

157.010186g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

157.010186g/mol

Rotatable Bond Count

If you have any other questions or need other size, please get a quote.