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  • Chitosan (20-100mPa·s, 0.5% in 0.5% Acetic Acid at 20°C)

  • Chitosan (20-100mPa·s, 0.5% in 0.5% Acetic Acid at 20°C)

    Catalog Number
    ACM9012764-5
    CAS Number
    9012-76-4
    Product Name
    Chitosan (20-100mPa·s, 0.5% in 0.5% Acetic Acid at 20°C)
    Category
    Polymers
    Description
    Solid
    IUPAC Name
    methyl N-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-5-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-[(2R,3S,4R,5R,6S)-5-amino-6-[(2R,3S,4R,5R,6R)-5-amino-4,6-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-4-hydroxy-6-(hydroxymethyl)oxan-3-yl]carbamate
    Molecular Weight
    1526.5g/mol
    Molecular Formula
    C56H103N9O39
    Canonical SMILES
    COC(=O)NC1C(C(C(OC1OC2C(OC(C(C2O)N)OC3C(OC(C(C3O)N)O)CO)CO)CO)OC4C(C(C(C(O4)CO)OC5C(C(C(C(O5)CO)OC6C(C(C(C(O6)CO)OC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)CO)OC9C(C(C(C(O9)CO)O)O)N)O)N)O)N)O)N)O)N)O)N)O
    InChI
    InChI=1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1
    InChI Key
    FLASNYPZGWUPSU-SICDJOISSA-N
    Application
    Chitosan (20-100mPa·s, 0.5% in 0.5% Acetic Acid at 20°C) serves a versatile purpose due to its unique properties as a film-forming polysaccharide, making it highly valuable in both cosmetic and pharmaceutical applications. This naturally derived basic polysaccharide enhances the skin's moisture retention by forming a barrier to prevent transepidermal water loss, while its ability to bind other ingredients helps increase the availability of active components to the skin. Known for its antibacterial properties, Chitosan also promotes the microbiological stability of formulations. It is widely used in moisturizers, sunscreens, acne treatments, and hair care products, contributing to improved skin softness and suppleness without feeling sticky. Derived from crustacean shells through the N-deacetylation of chitin, Chitosan possesses biodegradability, biocompatibility, and high adsorption capacity due to its -NH2 and -OH groups, which allow heavy metal ion chelation. In pharmaceutical contexts, Chitosan's potential spans across controlled drug delivery, mucoadhesive systems, peptide delivery optimization, and even gene delivery. It can be processed into gels, films, beads, microspheres, tablets, and liposome coatings through various methods such as spray-drying and coacervation, making it an integral component in innovative drug delivery systems.
    Complexity
    2630
    Covalently-Bonded Unit Count
    1
    EC Number
    618-480-0
    Exact Mass
    1525.635315g/mol
    Formal Charge
    0
    Heavy Atom Count
    104
    MeSH Entry Terms
    Chitosan;Poliglusam
    Monoisotopic Mass
    1525.635315g/mol
    Rotatable Bond Count
    27
    XLogP3
    -21.4
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