CAS 867062-95-1 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid, 97%

NAVIGATION

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid, 97%

PRICE INQUIRY

Catalog Number

ACM867062951

CAS Number

867062-95-1

Product Name

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid, 97%

Structure

Category

Polymers

IUPAC Name

3-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]propanoic acid

Molecular Weight

443.5g/mol

Molecular Formula

C24H29NO7

Canonical SMILES

C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCOCCOCCOCCC(=O)O

InChI

InChI=1S/C24H29NO7/c26-23(27)9-11-29-13-15-31-16-14-30-12-10-25-24(28)32-17-22-20-7-3-1-5-18(20)19-6-2-4-8-21(19)22/h1-8,22H,9-17H2,(H,25,28)(H,26,27)

InChI Key

CHIDDYZONKDHLG-UHFFFAOYSA-N

Application

1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13-tetraoxa-4-azahexadecan-16-oic acid, 97%, serves as a versatile reactant mainly used in Pegylation reactions, particularly for the synthesis of vaccines. This compound functions as a PEG linker featuring an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic polyethylene glycol (PEG) spacer enhances solubility in aqueous environments, facilitating various biochemical reactions. Upon basic treatment, the Fmoc group can be removed to expose a free amine, enabling further conjugation processes. Meanwhile, the terminal carboxylic acid group is reactive with primary amines, in the presence of activators such as EDC or HATU, to form stable amide bonds, making it an essential component in complex molecule assemblies.

Complexity

551

Covalently-Bonded Unit Count

Exact Mass

443.194402g/mol

Formal Charge

Heavy Atom Count

Monoisotopic Mass

443.194402g/mol

Rotatable Bond Count

XLogP3

2.1