2-Chlorotrityl Chloride Resin - Materials / Alfa Chemistry

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Resins

Resins for Solid Phase Peptide Synthesis

Unsubstituted Resins

2-Chlorotrityl Chloride Resin

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Catalog Number

ACMA00044145

Product Name

2-Chlorotrityl Chloride Resin

Structure

Category

Unsubstituted Resins

Synonyms

2-Cl-Trt chloride resin

Description

Amino acids can be attached to 2-Cl-Trt chloride resin with very little or no racemization. The steric bulk of 2-chlorotrityl chloride resin inhibits diketopiperazine formation, which can be a major side reaction in the synthesis of peptides with C-terminal proline.

Solubility

Insoluble in water

Application

2-Chlorotrityl chloride resin can be cleaved under extremely mild acid conditions that leave Boc/tBu based protecting groups in place. Thus it is used to prepare protected peptide fragments.

Color

Off-white.

Form

Solid

Packaging

25g, 100g

Size

100-200 mesh, 1% DVB

Storage Conditions

This product is stable. Conditions to Avoid: Hygroscopic; keep container tightly closed.

MSDS

Download MSDS