CAS 111-03-5 1-monoolein - Materials / Alfa Chemistry

NAVIGATION

1-monoolein

PRICE INQUIRY

Catalog Number

ACM111035

CAS Number

111-03-5

Product Name

1-monoolein

Structure

Category

Plasticizers

Synonyms

1-Monooleate glycerol

Description

DryPowder; Liquid; OtherSolid;OtherSolid;Liquid;pale yellow viscous oily liquid with a faint fatty odour

IUPAC Name

2,3-dihydroxypropyl (Z)-octadec-9-enoate

Molecular Weight

356.54

Molecular Formula

C21H40O4

Canonical SMILES

CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)O

InChI

InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-

InChI Key

RZRNAYUHWVFMIP-KTKRTIGZSA-N

Boiling Point

238-240 °C

Melting Point

35 °C

Purity

99%+

Density

0.9420 @ 20 °C/4 °C;0.925-0.935

Solubility

INSOL IN WATER; SOL IN ETHANOL, ETHER, CHLOROFORM;insoluble in water; soluble in hot organic solvents;soluble in hot alcohol (in ethanol)

Appearance

White powder

Application

1-monoolein serves a vital role in various applications due to its unique amphiphilic properties. As a polar lipid primarily accessed through glycerolysis or esterification of oleic acid, 1-monoolein manifests in different physical forms, from waxy solids to oily liquids, depending on its di- and tri-glyceride content. Notably characterized by its ability to swell in water and form multiple phases with distinct rheological properties, 1-monoolein is widely utilized in drug delivery systems for its biocompatibility, biodegradability, and minimal toxicity, earning it a status of 'generally recognized as safe' (GRAS). It facilitates the sustained release of water-soluble drugs, enhances transdermal and buccal drug absorption, and forms the basis of mucoadhesive drug delivery systems. Additionally, it is instrumental in the synthesis of cubosomes and serves as an effective emulsifier and stabilizer in both water-in-oil and oil-in-water emulsions. Its mucoadhesive properties and ability to form structured gel phases further extend its utility in optimizing drug administration and skincare formulations.

Storage

Freezer

Color/Form

PLATES FROM ETHANOL;YELLOW OIL OR SOFT SOLID

Complexity

315

Covalently-Bonded Unit Count

EC Number

203-827-7;247-038-6;266-951-0

Exact Mass

356.29266g/mol

Formal Charge

Heavy Atom Count

MeSH Entry Terms

1-oleoyl monoglyceride;1-oleoyl-2-glycerol;glycerol monooleate;glyceryl monooleate;glycerylmonooleate;mono-oleoylglycerol;monoelaidin;monolein;monoolein;myverol 18-99;oleic acid monoglyceride;sn-1-O-(cis-9)octadecenylglycerol

Monoisotopic Mass

356.29266g/mol

NSC Number

406285

Odor

SWEET

Other Experimental

MELTING POINT: 32 °C (UNSTABLE) /PRIMARY BETA FORM/; 35.5 °C (STABLE) /BETA FORM/;IODINE VALUE 65-80

Refractive Index

INDEX OF REFRACTION: 1.4626 @ 40 °C/D;1.462-1.468

Rotatable Bond Count

XLogP3